Pentosan Gold a pentosan polysulfate 250 mg/mL solution and Glucosamine 150 mg/mL in a 50 mL sterile glass vial.
Pentosan Gold is a concentrated 250 mg/mL anti-inflammatory, cartilage synthesis stimulant, and cartilage repair and protection agent.
The active ingredient in Pentosan Gold is polysulfate sodium (PPS), which is a polymer that has been enhanced to improve anti-inflammatory, fibrinolytic, and tissue trophic effects. Prepared from a plant extract, PPS is used to treat the effects of osteoarthritis in horses.
Pentosan Gold actively works to reduce the side effects of osteoarthritis in horse joints through a three-pronged approach:
1. By stimulating chondrocyte metabolism, Pentosan Gold increases production of proteoglycans, resulting in healthier cartilage. PPS stimulates production of viscous joint fluid, which improves fluid volume and consistency. Such effects result in more efficient joint lubrication and stabilization, thereby limiting further cartilage damage.
2. Pentosan Gold also acts as an inhibitory barrier to all factors contributing to joint inflammation. Its anti-inflammatory properties protect cartilage from degenerative mediators, preserving the cartilage and inhibiting the release of highly inflammatory elements. By combatting these chemical releases, Pentosan Gold helps relieve horse joint pain and inflammation.
3. PPS is a strong fibrinolytic that stimulates the release of activators that promote the dissolution of deposits in synovial tissues and subchondral blood vessels. Our Pentosan Gold formula is designed to increase the profusion of the joint, which results in the stimulation of cartilage healing and repair.
Pentosan Gold is used to counter the effects of non-infectious inflammatory joint disease, traumatic arthritis, degenerative cartilaginous joint disease, osteoarthritis and osteochondrosis dissecans in horses. Pentosan Gold is a sophisticated treatment approach to long-term relief and management of osteoarthritis in horses. Unlike traditional treatments, Pentosan Gold also promotes healthy joint healing, in addition to being a powerful anti-inflammatory. PPS actually directly stimulates healing and repairing of the joint, rather than acting as only an anti-inflammatory drug that simply masks symptoms while actually suppressing the early healing process of cartilage repair. While other drugs such as anti-inflammatories, corticosteroids, and NSAIDs relieve the symptoms of osteoarthritis, Pentosan Gold works to alter the disease process. Our formula has proven to be particularly effective with concurrent use of Cosequin Equine, a glucosamine and chondroitin sulfate supplement.
DOSAGE & ADMINISTRATION:
Administer through intravenous injection at a rate of 3 mg per kilogram of body weight (1.5 g per 500 kg horse) for 5 - 7 day intervals for four repetitions. If intra-articular use of Pentosan Gold is required, administer 1 mL through sterile injection.
Pentosan Gold (PPS) clings to cartilage, and active drug components will accumulate for several days after administration. For maximum effect, tissues should be exposed to the drug over an extended period, which is why four injections are recommended. It is required to allow up to a six month improvement period following a course of four injections to expect improvement. Pentosan Gold may be administered at any time during this period should the horse become sore after strenuous physical activity to calm inflammation.
Pentosan Gold should not be administered to horses with clotting defects, traumatic hemorrhage, infection, renal or hepatic failure, or those within 48 hours of surgery.
Our Pentosan Gold comes in a 50 mL sterile single dose glass vial that provides multiple doses for a 500 kg horse at the recommended dose rate (3 mg/kg).
STORAGE: Refrigeration is not required. Store below 25℃ and protect from light.