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ACTIONS- RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) causes a rapid release of the nerve system transmitters norepinephrine and serotonin from bound stores in the brain, subjecting them to rapid destruction by the body's own enzyme, monoamine oxidase (MOA). While "bound" the stores are not available to MOA. Norepinephrine and serotonin have potent effects on the metabolism of the brain. High levels (especially of norepinephrine) cause stimulation of cerebral activity and anxiety. Lowered levels depress cerebral activity resulting in relaxation and calmness. Norepinephrine and serotonin, on release from the bound stores, undergo rapid destruction by MOA. The net depletion of these substances creates the calming and relaxing effects of RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ). These effects continue for many days after administration, because levels are restored only slowly. INDICATIONS- RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) is particularly indicated where a prolonged effect to calm horses and reduce anxiety states is required, especially in the handling and management of dangerously anxious horses. Useful as an aid when unfamiliar surroundings and/or unaccustomed stress create anxiety in horses, and as a calming agent to aid in the training and education of stressed young horses.
RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) produces a prolonged calming effect without sedation, drowsiness, or loss of coordination, and vicious or dangerously anxious horses will become relaxed, sociable and co-operative with continued treatment.
RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) is indicated in any situation where stress/anxiety in horses is difficult to manage. Before using on horses that will be involved in competitive activities, the pre-competition withdrawal period should be ascertained (this may vary from one country to another depending on laboratory methods used for substance detection). FORM- Sterile for injection ??? CATEGORY- Sedatives & Calming Agents ??? FOR- Horses, Greyhounds, Dogs, Camels DOSEAGE & ADMINISTRATION - Give RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) by intramuscular injection only. The dose administered must be sufficient to deplete Norepinephrine and Serotonin stores. Because the initial levels of these stores will vary from horse to horse, the veterinarian must be prepared to vary the dose to achieve optimum efficacy. A useful clinical sign is the brief period of diarrhea, which accompanies the initial release of bound Serotonin before its destruction by MOA. This period of increased bowel activity is a reliable indicator that the desired behavioral response should follow.
Adult Horses: 1 - 4 mL weekly, or as directed by a veterinary surgeon. Give by intramuscular injection only. ??? Some veterinarians advise giving 2 - 4 ml on alternate days until desired response is achieved. ??? Then repeat injections of 2 - 4 mL at 4 - 8 day intervals. This dosage regime may be altered to suit the individual animal response. Lack of response is almost always the result of under dosing.
PRESENTATION - 20mL sterile glass multi-dose vial for intramuscular injection ??? STORAGE - Store below 25 C (Air Conditioning) Store below 25oC (air conditioning). Protect from light. ??? AVAILABILTY - For General Sale ???APVMA Approval Number 51452 ??? NOTES- This product can be used with any other Vitamin or supplement from HorsePreRace. This product is best used the day before and the day of event. This product compares to Nature Vet Rakelin in that both have the same ingredients. ??? This product is not manufactured or distributed by Nature Vet who is the sole distributor of Rakelin ??? These statements have not been evaluated by the Food and Drug ??? Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. WARNINGS - RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) may produce penile relaxation. Stallions which have been treated with RESERPINE INJECTION (Compare to the active ingredients of Nature Vet Rakelin ) should not be used to serve mares for at least 14 days following injection.